Neocutis PSP vs. SkinMedica TNS – What Makes Their Blends Unique?

By now, you’ve probably realized the importance of investing in tried-and-tested skincare products. Now, you’ll find out what makes these two brands special in this Neocutis PSP vs. SkinMedica TNS article.

If you recently just discovered that your skin isn’t as forgiving as it was in your youth, then join the team! Ever since I noticed the changes, I’d spend more time in the mirror worrying and stressing on how to slow down the process. It doesn’t matter how young you feel in your heart; once you notice the lines and wrinkles, you realize you may not be that young anymore.

Enter the powerhouse brands in the cosmetic/dermatology world. Once you recognize that the regular moisturizer, toner, and treatment routine you’re used to isn’t enough, you understand why thousands (if not millions) of women spend insane amounts of money on certain skincare lines and anti-aging products. Neocutis and SkinMedica are some of the trusted brands, and you’ll find out why.

Differences Between Neocutis PSP and SkinMedica TNS

Primary Complex
PSP (Processed Skin cell Proteins)
TNS (Tissue Nutrient Solution)
Star Product

Neocutis PSP vs. SkinMedica TNS – A Quick Comparison

Patented Formulations

High-end brands like SkinMedica and Neocutis have their distinctive concoctions that make their products a lot more effective than most. For Neocutis, PSP is the first and the most popular of the patented technologies (others include ROSAPLEX, VITAPLEX, and more). The PSP blend contains polypeptides and proteins that nourish and activate growth factors and cytokines responsible for nourishing your skin – you can find it in a number of the Neocutis lines.

SkinMedica’s TNS complex is a lot similar to Neocutis PSP. However, TNS was the first in the skincare scene, paving the way for topical human growth factor solutions for brands like Neocutis. According to the company, SkinMedica’s patented TNS has the highest concentration (almost 94%) of over 350 growth factors, matrix proteins, and cytokines.


Since the individual formulations were such a hit, both brands used them in some of their products. An array of the Neocutis Journée lines, Lumiere lines, Bio Creams, Bio Gels, and Bio Serums contain PSP. If you’re interested in a different formulation, Neocutis has other products containing the rest of the special technologies.

SkinMedica featured fewer but potent products with the TNS formulation. They include some of the recovery complex, eye repair serums, eye creams, and treatments. However, you can find other SkinMedica products with different but very effective ingredients; like Retinol and Hyaluronic acid.


For such pricey brands, proving the value and safety of the products is essential for anyone willing to spend a load of money on them. According to a study on the use of PSP in skincare products, there were improvements in skin tightness, wrinkles, texture, tone, hydration, and all the users liked the feel of the product on the skin. It’s safe to say Neocutis had it right when they invested in PSP.

Knowing that the co-founder of SkinMedica was a dermatologist makes you know that your skin is in safe hands. SkinMedica has done lots of clinical studies, research, and surveys, and the results were amazing. Over 90% of the users were pleased with the changes they experienced.

Neocutis Journée Day Cream Review

Neocutis Journee.jpg

Journée is an intense day cream for women interested in multitasking on skin care. Apart from PSP, the cream contains Vitamins C and E, Melanin, Hyaluronic acid, 7.3% Zinc Oxide, 7.5% Octinoxate, and Glycerin. Together, you get skin hydration, antioxidant care, UVA/UVB protection, and overall revitalization.

After your regular cleansing, toning, and eye and neck cream application follow up with the Journée Day Cream in the morning. If you’re using it for sunscreen purposes, apply generously about 15 minutes before you walk out, and reapply every two hours. For swimming or sweaty activities, pair with a water-resistant sunscreen.


  • Special PSP complex
  • Multitasking abilities for all-rounded skin care


  • Occasional defective pumps


View price on Amazon


SkinMedica TNS Essential Serum Review

SkinMedica TNS Essential.jpg

A quick look at the TNS Essential Serum price tag is enough to make your head spin. However, that’s because the bottle contains two different products – The TNS Recovery Complex and the APS Corrective Complex separated by two chambers inside. While one product improves your lines, wrinkles, tone, and texture, the other works on fighting free radical damage and support skin health.

After cleansing and toning, dispense the serum on the back of your hand and blend before applying to your skin. Apply in the morning and evening on your face (neck and chest too, if you desire), or as skincare professional would advise. Use the TNS Essential Serum before other products.


  • Special TNS Complex
  • Two powerful products in one


  • The bottle frequently clogs up, leaving you with no option but to remove the cap


View price on Amazon



Simply hearing your friend’s opinion on one product isn’t enough to help you purchase unless you have the exact skin profile! I compared Neocutis PSP vs. SkinMedica TNS to give you an in-depth view on what the formulations do. Though I can’t tell you what is best for you, I’d recommend SkinMedica TNS for pioneering the growth factor complex and the dedication to giving you high-quality medical-grade creations.

FAQ Section

What is PSP in Neocutis?

PSP stands for Processed Skin Cell Proteins. PSP is a Neocutis technology designed to aid in nourishing and minimizing aging signs on the skin.

What is Neocutis Journee?

Journee is a PSP-containing day cream by Neocutis. It helps restore moisture, nourish, and also protect your skin from harmful UV rays.

What is in SkinMedica TNS?

TNS in SkinMedica products stands for Tissue Nutrient Solution. It is a special complex that provides human growth factors, peptides, and more vital ingredients to rejuvenate your skin.

What is the difference between TNS Recovery Complex and TNS Essential Serum?

TNS Recovery Complex is a stand-alone skincare product by SkinMedica. TNS Essential Serum, on the other hand, contains both the TNS Recovery Complex and the APS Corrective Complex.

Marie Stevenson

Having been a victim of counterfeit products Marie Stevenson decided to comb various markets both online and physical to find the best original beauty products for women. The influx of counterfeits is palpitation inducing especially when you consider the aftermath. The consequences of using fake makeup or tanning lotions can be quite expensive and life-threatening and the reason why Marie decided to provide you with insightful information that will actually enhance your health. Apart from saving the world from the influx of fake beauty products Marie is a dedicated environmentalist, loves to travel and read. Her famous line is that if you believe it and have the passion to do something right then don’t let someone else discourage since they don’t understand where you are coming from.

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