SkinMedica TNS vs Neocutis – A helpful illustrated guide

SkinMedica TNS is the first product in the skincare industry to help slow down your skin’s aging process and help it heal from within. The SkinMedica TNS vs Neocutis comparison will give you a clear picture of the two products.

I have been using .01% tretinoin as prescribed by my dermatologist for treating acne and some fine lines. I followed every instruction to the letter and used the recommended products for moisturizing day and night and never forgot to put sunscreen. But to be honest it’s been over 2 months now and my acne hasn’t completely gone especially on my forehead. Then I noticed the texture of my skin has changed like overnight, there are more fine lines than before and I have huge pores. I have continued using tretinoin but it’s getting worse. I don’t know which product to use but maybe the SkinMedica vs Neocutis comparison can help.

Here is a table comparison between SkinMedica TNS and Neocutis

Human growth factors
Contains Nouricel MD, a complex that contains human growth factors and cytokines.
Processed Skin Cell Proteins, PSP, which is from fetal fibroblasts.
It takes long to reach underneath the skin.
Strong medicinal smell that lingers for long.
Is an odourless serum
Natural antioxidants that help reduce free radical damage.

SkinMedica TNS vs Neocutis – How do they differ?

Human growth factors and cytokines

SkinMedica TNS contains Nouricel MD, a complex that contains human growth factors and cytokines. It’s an ingredient that was got from bioengineered human skin which contains different natural human growth factors and other essential compounds that are produced by healthy new skin. Neocutis contains Processed Skin Cell Proteins, PSP, which is from fetal fibroblasts.


Apart from the human growth factors in both products, SkinMedica TNS also contains collagen which is not a helpful ingredient in the product because it’s too large to pass through the dermis of your skin to reach the layers that contain collagen underneath your skin.


SkinMedica TNS and Recovery complex have very strong smells that might put you off. It has a medicinal smell that lingers on your face for a long time. As for Neocutis Bio-cream and Bio-serum are quite odourless.


SkinMedica TNS contains antioxidants that help to reduce the damage done on your skin by free radicals in the environment. These are natural antioxidants that are rich in polyphenols that work together with vitamin E to repair your skin.

SkinMedica TNS vs Neocutis comparison reviews

SkinMedica TNS


SkinMedica TNS Essential Serum is an all-in-one skin care regimen that combines the TNS Recovery Complex growth factor formula and the APS Corrective Complex in separate individual chambers. Its aim is to hydrate and firm your skin while enhancing its texture, skin tone, and reduce the wrinkles and fine lines.

APS Corrective Complex contains antioxidants like green tea extract and blackberry and peptides that enhance the overall appearance of your skin while TNS Recovery Complex contains growth, proteins, and antioxidants that reduce fine lines and wrinkles. Within a month you will have a more youthful skin that is rejuvenated and having an even skin tone. You can apply the serum every day morning and evening after you have cleansed and toned your skin.


  • Antioxidants help to reduce the damage caused by free radicals.
  • Peptides strengthen and improve your overall skin appearance.
  • Alpha-arbutin that brightens discoloration on your skin and dark spots.
  • Hyaluronic acid keeps your skin hydrated by trapping the moisture on your skin surface.


  • Can affect sensitive skin.
  • Quite expensive.


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Neocutis is a skin care product that is formulated with processed skin cell proteins PSP, a human growth factor that helps to reverse your aging process leaving your skin healthier and younger. The Bio-serum contains collagen amino acids that help to firm your skin and reduce wrinkles and fine lines. The Bio-serum has concentrated amounts of PSP that is aimed at nourishing your skin to give you a firm, youthful skin with a supple look. It softens your fine lines improving signs of aging, hydrates your skin, and the best part is it’s gentle and safe enough to be used around your eyes.

The Bio-cream evens out your skin tone and texture giving you a smoother and youthful complexion. The formulation of the cream is gentle which is safe to be applied on all skin types and on post-procedure skin.


  • Diminishes fine lines and wrinkles.
  • Improves your skin texture and skin tone.
  • Firms your skin and enhances its appearance.
  • Safe for post-procedures and sensitive skin.
  • Hydrates your skin for a youthful appearance.


  • Bio-cream contains fetal fibroblasts.


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So, which produce among the two is better?

As far as human growth factors and cytokines are concerned, both SkinMedica TNS and Neocutis have shown to be very effective in producing desired results when it comes to reducing fine lines, wrinkles, and discolouration. However, SkinMedica TNS has a bit of an advantage because it specifies the human growth factors and cytokines present but Neocutis doesn’t. SkinMedica TNS is very easy to use and apply in the morning and evening but it’s a bit more expensive than Neocutis.


How long does TNS Essential serum last?

According to clinical studies conducted, you will start to notice some results after 30 days and optimal results in 90 days. You can use TNS Essential serum for as long as you want to improve your overall appearance.

How long does TNS Recovery Complex last?

If applied twice a day as directed, TNS Recovery Complex should last for 30 days. You apply it on your face, neck, or chest if you want.

Does TNS serum have vitamin C?

TNS Recovery complex contains a stable form of ascorbic acid or vitamin C which is a great antioxidant. It also contains vitamin E which is also an antioxidant that helps to reduce the effects of free radicals on your skin.

What is the TNS Recovery Complex?

TNS which stands for Tissue Nutrient System is an anti-aging serum that is formulated to reduce inflammation, encourage cell growth, and give you a healthier, youthful, and glowing skin.

What is bio cream?

This is the original skin cream made from PSP which contains proteins from human growth factors and cytokines to rejuvenate and soothe your skin. It’s a cream suitable for all skin types to reduce fine lines and wrinkles.


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